A little tip, how to enable globally jumbo frames on a Cisco Nexus 5k switch?

Let's say you want to set the MTU to the maximum size, that means 9216 :

sw-nx-n1# conf
Enter configuration commands, one per line.  End with CNTL/Z.
sw-nx-n1(config)# policy-map type network-qos jumbo
sw-nx-n1(config-pmap-nq)# class type network-qos class-default
sw-nx-n1(config-pmap-nq-c)# mtu 9216
sw-nx-n1(config-pmap-nq-c)# exit
sw-nx-n1(config-pmap-nq)# exit
sw-nx-n1(config)# system qos
sw-nx-n1(config-sys-qos)# service-policy type network-qos jumbo
sw-nx-n1(config-sys-qos)# copy run start

And everything should be fine!

Note: I did this multiple times on Nexus 5000 series switches, work like a charm, not sure if it's exactly the same with others Nexus family (3000, 7000...).

Source : Cisco Nexus 5000 Series NX-OS Quality of Service Configuration Guide